Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853831 | 0.94 | NR1I2 (0.41) | NR1I2PGRKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL10851072 | 0.94 | NR1I2 (0.41) | NR1I2PGRKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL10853731 | 0.93 | NR1I2 (0.36) | NR1I2PGRKCNH2HSD17B10TDP1 | |
| SCHEMBL10848808 | 0.92 | KMT2A (0.36) | NR1I2PGRKCNH2HSD17B10MAPT | |
| SCHEMBL10859765 | 0.92 | NR1I2 (0.39) | NR1I2PGRKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL11357586 | 0.91 | NR1I2 (0.49) | NR1I2PGRKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL10850515 | 0.91 | NR1I2 (0.41) | NR1I2PGRKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL10851717 | 0.90 | KCNH2 (0.34) | NR1I2PGRKCNH2HSD17B10TDP1 | |
| SCHEMBL10840189 | 0.90 | NR1I2 (0.42) | NR1I2PGRKCNH2ALDH1A1HSD17B10 | |
| SCHEMBL10857983 | 0.89 | NR1I2 (0.42) | NR1I2PGRKCNH2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567275-A | 2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)GLYOXYLIC ACID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4468515-A | CEPRALOSPORINS, MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4425340-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4390534-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4332798-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |