Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.64 |
| ▸ | MGAM | O43451 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SI | P14410 | 2/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847442 | 0.87 | PDE2A (0.64) | PDE2AMGAMGAASIMGAM2 | |
| SCHEMBL10844083 | 0.86 | PDE2A (0.62) | PDE2AMGAMGAASIMGAM2 | |
| SCHEMBL10846727 | 0.86 | PDE2A (0.62) | PDE2AMGAMGAASIMGAM2 | |
| SCHEMBL10846574 | 0.86 | PDE2A (0.62) | PDE2AMGAMGAASIMGAM2 | |
| SCHEMBL11770981 | 0.78 | PDE2A (1.00) | PDE2AKDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL10609335 | 0.78 | PDE2A (0.50) | PDE2AMGAMGAASIMGAM2 | |
| Hydrochloric Acid SCHEMBL11769751 | 0.77 | PDE2A (0.97) | PDE2AKDM4EHSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL7270959 | 0.75 | PDE2A (0.58) | PDE2AGAAKDM4ECYP1A2SMN1; SMN2 | |
| SCHEMBL10742148 | 0.75 | PDE2A (0.68) | PDE2AGAAKDM4EHSD17B10CYP1A2 | |
| SCHEMBL7280668 | 0.74 | PDE2A (0.57) | PDE2AMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4603139-A | 2-PHENYL-1H-IMIDAZOL(4,5-C)PYRIDINES, ANTICXOAGULANTS, CARDIOVASCULAR DISORDERS | BURROUGHS WELLCOME CO. | 1986-07-29 | — | — | US | disclosed |
| EP-0079083-A1 | New imidazo[4,5-c]pyridine derivatives, processes for their preparation and pharmaceutical formulations containing such compounds | MERCK PATENT GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |