Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 3/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.53 |
| ▸ | ITGAL | P20701 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | GGT1 | P19440 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23787378 | 0.82 | ITGB2 (0.56) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL1133307 | 0.82 | ITGB2 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL14028689 | 0.82 | ITGB2 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL1132649 | 0.82 | ITGB2 (0.57) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL28684251 | 0.81 | ITGB2 (0.56) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL151336 | 0.80 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL27413426 | 0.80 | ITGB2 (0.67) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL163397 | 0.80 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL27043238 | 0.80 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP3A4SLC7A5 | |
| SCHEMBL28386295 | 0.80 | ITGB2 (0.60) | ITGB2ICAM1ITGALCYP3A4SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616081-A | ANTIBIOTIC, BACTERICIDE WITH GOOD ABSORTION AND STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0098609-A2 | Novel cephalosporin compounds | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-01-18 | — | — | EP | disclosed |