Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | NME2 | P22392 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10850154 | 1.00 | KMT2A (0.52) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10851724 | 0.94 | KMT2A (0.53) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10851710 | 0.94 | KMT2A (0.53) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10856918 | 0.93 | KMT2A (0.50) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10856930 | 0.93 | KMT2A (0.50) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10856939 | 0.93 | KMT2A (0.50) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10853602 | 0.91 | KMT2A (0.62) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10853596 | 0.91 | KMT2A (0.62) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10850968 | 0.90 | KMT2A (0.56) | KMT2AMAPTALDH1A1MCL1NPSR1 | |
| SCHEMBL10850955 | 0.90 | KMT2A (0.56) | KMT2AMAPTALDH1A1MCL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579847-A | Amino derivatives of benzylidene-pyrrolo[2,1-b]quinazolines useful for treating conditions of allergic origin | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-04-01 | — | — | US | disclosed |