Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851962 | 0.95 | NR1I2 (0.34) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10839050 | 0.95 | KCNH2 (0.38) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10852357 | 0.94 | NR1I2 (0.34) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10839018 | 0.94 | NR1I2 (0.40) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10857687 | 0.93 | KCNH2 (0.34) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10856327 | 0.93 | NR1I2 (0.33) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10853405 | 0.93 | NR1I2 (0.34) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10855516 | 0.93 | NR1I2 (0.34) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10854213 | 0.93 | NR1I2 (0.35) | NR1I2PGRKCNH2L3MBTL1 | |
| SCHEMBL10854628 | 0.92 | NR1I2 (0.33) | NR1I2PGRKCNH2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567275-A | 2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)GLYOXYLIC ACID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-28 | — | — | US | disclosed |
| US-4468515-A | CEPRALOSPORINS, MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4425340-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4390534-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4332798-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |