SCHEMBL108530

SCHEMBL108530

CCCCCC(O)CC=CO

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.51
FFAR4 Q5NUL3 2/20 0.51
FAAH O00519 2/20 0.44
GPR84 Q9NQS5 8/20 0.44
NFKB1 P19838 2/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
TRPA1 O75762 1/20 0.38
DDAH1 O94760 1/20 0.38
GAPDH P04406 1/20 0.38
MAPT P10636 1/20 0.38
PSMD14 O00487 2/20 0.38
PLA2G1B P04054 2/20 0.38
MMP2 P08253 2/20 0.38
ATG4B Q9Y4P1 2/20 0.38
HSP90AA1 P07900 1/20 0.38
RAD52 P43351 1/20 0.38
SPHK1 Q9NYA1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108529 1.00 FFAR1 (0.51) FFAR1FFAR4FAAHGPR84NFKB1
SCHEMBL3134939 0.98 FFAR1 (0.54) FFAR1FFAR4FAAHGPR84NFKB1
SCHEMBL3134932 0.98 FFAR1 (0.54) FFAR1FFAR4FAAHGPR84NFKB1
SCHEMBL10583720 0.93 FFAR1 (0.45) FFAR1FFAR4FAAHGPR84NFKB1
SCHEMBL10583718 0.93 FFAR1 (0.45) FFAR1FFAR4FAAHGPR84NFKB1
SCHEMBL449788 0.86 FFAR1 (0.64) FFAR1FFAR4FAAHGPR84NFKB1
SCHEMBL449789 0.86 FFAR1 (0.64) FFAR1FFAR4FAAHGPR84NFKB1
SCHEMBL16502016 0.84
SCHEMBL11193975 0.83 FFAR1 (0.56) FFAR1FFAR4FAAHGPR84NFKB1
SCHEMBL26090214 0.83 FFAR1 (0.56) FFAR1FFAR4FAAHGPR84NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114829004-A Method for preparing Ni-X-based oxide catalyst and application thereof in transfer hydrogenation 中国科学院青岛生物能源与过程研究所 2022-07-29 CN claimed
US-8030010-B2 Method for detecting a biomarker of oxidative stress in a biological sample INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) 2011-10-04 US claimed
US-20090111121-A1 METHOD FOR DETECTING A BIOMARKER OF OXIDATIVE STRESS IN A BIOLOGICAL SAMPLE INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) 2009-04-30 US claimed
CN-101379396-A Method for detecting biomarkers of oxidative stress in biological samples INST CARDIOLOGIE MONTREAL (CA) 2009-03-04 CN claimed
US-20030153483-A1 Concentrated, stable fabric softening composition TRINH TOAN (US) 2003-08-14 US claimed
EP-0842250-A1 CONCENTRATED, STABLE FABRIC SOFTENING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1998-05-20 EP claimed
WO-1997003169-A1 CONCENTRATED, STABLE FABRIC SOFTENING COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1997-01-30 WO claimed
EP-3510014-B1 COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NASH OR ALD METABOLIC TECH INC (US) 2026-04-29 EP disclosed
US-20260102458-A1 METHODS OF TREATING LONG TERM CORONAVIRUS INFECTION UNIV MIAMI (US) 2026-04-16 US disclosed
CN-116601159-B Prodrug of aldehyde ketone reductase inhibitor, pimestat disulfide, preparation, pharmaceutical composition and application thereof 斯洛伐克科学院实验医学中心 2026-02-27 CN disclosed
US-20250360094-A1 COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER MTI BIOTECH INC (US) 2025-11-27 US disclosed
US-20250263433-A1 METHODS FOR REDUCING CD36 EXPRESSION CORNELL RESEARCH FOUNDATION, INC. (US) 2025-08-21 US disclosed
US-12383515-B2 Compositions and methods of use of γ-ketoaldehyde scavengers for treating, preventing or improving nonalcoholic fatty liver disease (NAFLD), NASH, ALD or conditions related to the liver MTI BIOTECH, INC. (US) 2025-08-12 US disclosed
EP-1558585-A1 NEUROLOGICALLY-ACTIVE COMPOUNDS Prana Biotechnology Ltd (AU) 2005-08-03 EP disclosed
EP-1539700-A1 8-HYDROXY QUINOLINE DERIVATIVES Prana Biotechnology Ltd (AU) 2005-06-15 EP disclosed
WO-2004087160-A1 TREATMENT OF NEUROLOGICAL CONDITIONS PRANA BIOTECHNOLOGY LTD (AU) 2004-10-14 WO disclosed
US-20040101521-A1 Iron sequestration or elimination to reduce neurodegeneration or Parkinsons disease progression THE BUCK INSTITUTE FOR RESEARCH ON AGING 2004-05-27 US disclosed
WO-2004031161-A1 NEUROLOGICALLY-ACTIVE COMPOUNDS PRANA BIOTECHNOLOGY LIMITED (AU) 2004-04-15 WO disclosed
WO-2004006856-A2 IRON SEQUESTRATION OR ELIMINATION TO REDUCE NEURODEGENERATION OR PARKINSONS DISEASE PROGRESSION THE BUCK INSTITUTE FOR RESEARCH ON AGING (US) 2004-01-22 WO disclosed
WO-2004007461-A1 8-HYDROXY QUINOLINE DERIVATIVES PRANA BIOTECHNOLOGY LIMITED (AU) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102458-A1 METHODS OF TREATING LONG TERM CORONAVIRUS INFECTION ACE2, ACE, MICA FFAR1 3352/4885FFAR4 3805/4885FAAH 3018/4885
US-12383515-B2 Compositions and methods of use of γ-ketoaldehyde scavengers for treating, preventing or improving nonalcoholic fatty liver disease (NAFLD), NASH, ALD or conditions related to the liver AKR7A2, CPT1A, FABP1 FFAR1 242/4885FFAR4 586/4885FAAH 456/4885
US-20250360094-A1 COMPOSITIONS AND METHODS OF USE OF GAMMA-KETOALDEHYDE SCAVENGERS FOR TREATING, PREVENTING OR IMPROVING NONALCOHOLIC FATTY LIVER DISEASE (NAFLD), NASH, ALD OR CONDITIONS RELATED TO THE LIVER CPT1A, AKR7A2, FABP1 FFAR1 247/4885FFAR4 587/4885FAAH 422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.