Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.64 |
| ▸ | CNR2 | P34972 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660791 | 0.88 | CNR1 (0.66) | CNR1CNR2LMNAGMNNCYP1A2 | |
| SCHEMBL9037475 | 0.84 | CNR1 (0.70) | CNR1CNR2LMNAGMNNCYP1A2 | |
| SCHEMBL9035533 | 0.84 | CNR1 (0.66) | CNR1CNR2LMNAGMNNCYP1A2 | |
| SCHEMBL9691719 | 0.84 | CNR1 (0.66) | CNR1CNR2LMNAGMNNCYP1A2 | |
| SCHEMBL10738511 | 0.83 | CNR1 (0.69) | CNR1CNR2LMNAGMNNCYP1A2 | |
| SCHEMBL17414512 | 0.83 | CNR2 (0.74) | CNR1CNR2 | |
| SCHEMBL9689406 | 0.82 | CNR1 (0.58) | CNR1CNR2LMNAGMNNCYP1A2 | |
| SCHEMBL15995414 | 0.80 | CNR1 (0.64) | CNR1CNR2LMNAGMNNCYP1A2 | |
| SCHEMBL8532949 | 0.79 | CNR1 (0.69) | CNR1CNR2CYP1A2CYP3A4TSHR | |
| SCHEMBL9302795 | 0.79 | CNR1 (0.62) | CNR1CNR2LMNAGMNNCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581354-A | ANALGESICS;ANTI-RHEUMATIC AND ANTI-INFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1986-04-08 | — | — | US | claimed |