Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012444 | 0.83 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27347606 | 0.83 | GAA (0.52) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL966840 | 0.81 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3365530 | 0.81 | GAA (0.50) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2583703 | 0.79 | CA12 (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13480885 | 0.79 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3292956 | 0.79 | GAA (0.48) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL12959650 | 0.78 | GAA (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL27362485 | 0.77 | CA12 (0.33) | GAAALDH1A1CA12CA2SMN1; SMN2 | |
| SCHEMBL24876686 | 0.76 | GAA (0.45) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595532-A | N-(substituted-methyl)-azetidin-2-ones | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0116432-A2 | Improvements in or relating to N-(substituted-methyl)-azetidin-2-ones | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-08-22 | — | — | EP | disclosed |