Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | RAD52 | P43351 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996505 | 0.82 | ADORA1 (0.62) | ALDH1A1ADORA1KDM4EMAPTKMT2A | |
| SCHEMBL8289394 | 0.81 | ADORA1 (1.00) | ALDH1A1ADORA1KDM4EMAPTRAD52 | |
| SCHEMBL10856568 | 0.78 | ADORA1 (0.69) | ALDH1A1ADORA1KDM4EMAPTRAD52 | |
| SCHEMBL29229875 | 0.78 | ADORA1 (0.68) | ALDH1A1ADORA1KDM4EMAPTRAD52 | |
| SCHEMBL10862455 | 0.77 | MAPT (0.80) | ALDH1A1ADORA1KDM4EMAPTRAD52 | |
| SCHEMBL10856539 | 0.75 | ADORA1 (0.68) | ALDH1A1ADORA1KDM4EMAPTRAD52 | |
| SCHEMBL29229884 | 0.74 | ADORA1 (0.62) | ALDH1A1ADORA1KDM4EMAPTRAD52 | |
| SCHEMBL14648848 | 0.73 | KMT2A (0.61) | ALDH1A1MAPTRAD52KMT2AMEN1 | |
| SCHEMBL17194236 | 0.72 | MAPT (1.00) | ALDH1A1ADORA1KDM4EMAPTKMT2A | |
| SCHEMBL30222268 | 0.72 | MAPT (0.61) | ALDH1A1ADORA1KDM4EMAPTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575504-A | BRADYCARDIACS | DR. KARL THOMAE GMBH (DE) | 1986-03-11 | — | — | US | disclosed |