SCHEMBL10857

SCHEMBL10857

On1ccc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.50
CCND1 P24385 4/20 0.50
NOTUM Q6P988 1/20 0.48
KMT2A Q03164 2/20 0.45
TSHR P16473 2/20 0.45
RAB9A P51151 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
BIRC5 O15392 1/20 0.42
LMNA P02545 2/20 0.41
PRKD3 O94806 1/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCA P17252 1/20 0.41
PRKACA P17612 1/20 0.41
PRKACG P22612 1/20 0.41
PRKACB P22694 1/20 0.41
PRKCH P24723 1/20 0.41
PRKCI P41743 1/20 0.41
PRKCE Q02156 1/20 0.41
PRKCQ Q04759 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363836 1.00 CDK4 (0.50) CDK4CCND1NOTUMKMT2ATSHR
Water SCHEMBL7404361 0.97 CDK4 (0.48) CDK4CCND1NOTUMKMT2ATSHR
Iodide SCHEMBL30440525 0.97 CDK4 (0.48) CDK4CCND1NOTUMKMT2ATSHR
Hydrochloric Acid SCHEMBL28218480 0.97 CDK4 (0.48) CDK4CCND1NOTUMKMT2ATSHR
Hydrochloric Acid SCHEMBL28859818 0.95 CDK4 (0.46) CDK4CCND1NOTUMKMT2ATSHR
Acetic Acid SCHEMBL1747615 0.87 NOTUM (0.58) CDK4CCND1NOTUMKMT2ATSHR
Ethylamine SCHEMBL5479388 0.87 CDK4 (0.45) CDK4CCND1NOTUMKMT2ATSHR
Acetaldehyde SCHEMBL17261300 0.87 NOTUM (0.48) CDK4CCND1NOTUMKMT2ATSHR
Ethoxycarbonyl Group SCHEMBL27580247 0.77 NOTUM (0.40) CDK4CCND1NOTUMKMT2ATSHR
Valine SCHEMBL1397937 0.76 SLC7A5 (0.46) NOTUMKMT2ATSHRRAB9AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2599 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001345-B1 DEGRADABLE HYPERBRANCHED RESIN, PREPARATION METHOD THEREFOR, AND USE THEREOF UNIV SOUTH CHINA TECH (CN) 2026-04-01 EP claimed
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
CN-120081486-A Indolyl porous Fenton reagent, preparation method thereof and application thereof in Fenton reaction 西南科技大学 2025-06-03 CN claimed
WO-2024258193-A1 METAL-PHENOL COMPLEX AND DYEING COMPOSITION COMPRISING MELANIN OR PRECURSOR THEREOF 코스맥스 주식회사 2024-12-19 WO claimed
CN-116444535-B Electrolyte with visible light response and preparation method and application thereof 五邑大学 2024-10-18 CN claimed
WO-2024190663-A1 BIOMARKER AND USE THEREOF 株式会社明治 2024-09-19 WO claimed
WO-2024183472-A1 ELECTROLYTE HAVING VISIBLE LIGHT RESPONSE, PREPARATION METHOD THEREFOR, AND USE THEREOF 五邑大学 2024-09-12 WO claimed
CN-118530332-A Preparation method of pramlintide 南京羚诺生物医药技术研究院有限公司 2024-08-23 CN claimed
CN-115701440-B Polyimide composite film, preparation method thereof and electronic equipment 华为技术有限公司 2024-07-30 CN claimed
US-20240216524-A1 Chemoselective Rapid Azo-Coupling Reaction for Bioconjugation TRUSTEES BOSTON COLLEGE (US) 2024-07-04 US claimed
US-4776857-A HYDROXYINDOLES AND PERIODATE OXIDIZERS; HAIR AND SKIN REPLIGEN CORPORATION (US) 1988-10-11 US claimed
EP-0271186-A1 Hydroxyindoles and their use in dyeing REPLIGEN CORPORATION (US) 1988-06-15 EP claimed
US-4711893-A Use of hydroxyindole derivatives in lowering blood pressure MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-12-08 US claimed
EP-0241654-A1 Hydroxyindole esters MERCK PATENT GmbH (DE) 1987-10-21 EP claimed
US-4598033-A IMPROVED SENSITIVITY AND DURAVILITY FUJI PHOTO FILM CO., LTD. (JP) 1986-07-01 US claimed
US-4360464-A Process for production of 1-aryloxy-aminopropane derivatives TEIKOKU HORMONE MFG. CO. LTD. (JP) 1982-11-23 US claimed
EP-0015523-B1 INDOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE FOR MEDICAMENTS Dr. Karl Thomae GmbH (DE) 1982-10-13 EP claimed
US-4302448-A Secretin preparations with intensified and protracted action, process for their manufacture, their use as well as dihydroxybenzoyl-L-tyrosine HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-24 US claimed
US-4263397-A SEALING A PACKAGE OF FILM HAVING A SILVER HALIDE EMULSION LAYER CONTAINING A SENSITIZING OR DESENSITIZING DYE; OXYGEN PERMEABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-04-21 US claimed
EP-0015523-A1 Indole derivatives, their preparation and their use for medicaments Dr. Karl Thomae GmbH (DE) 1980-09-17 EP claimed