Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | NME2 | P22392 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10857176 | 1.00 | MEN1 (0.54) | MEN1KMT2ANME2ALOX5 | |
| SCHEMBL10857187 | 1.00 | MEN1 (0.54) | MEN1KMT2ANME2ALOX5 | |
| Dimethylamine SCHEMBL10858458 | 0.97 | MEN1 (0.51) | MEN1KMT2ANME2ALOX5 | |
| SCHEMBL10853628 | 0.93 | MEN1 (0.62) | MEN1KMT2ANME2 | |
| SCHEMBL10853654 | 0.93 | MEN1 (0.62) | MEN1KMT2ANME2 | |
| SCHEMBL10853641 | 0.93 | MEN1 (0.62) | MEN1KMT2ANME2 | |
| SCHEMBL10853970 | 0.93 | MEN1 (0.55) | MEN1KMT2ANME2 | |
| SCHEMBL10849660 | 0.93 | MEN1 (0.54) | MEN1KMT2ANME2 | |
| SCHEMBL10849666 | 0.93 | MEN1 (0.54) | MEN1KMT2ANME2 | |
| SCHEMBL10849672 | 0.93 | MEN1 (0.54) | MEN1KMT2ANME2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579847-A | Amino derivatives of benzylidene-pyrrolo[2,1-b]quinazolines useful for treating conditions of allergic origin | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-04-01 | — | — | US | disclosed |