Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HK2 | P52789 | 5/20 | 0.43 |
| ▸ | HK1 | P19367 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | PYGB | P11216 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674579 | 0.86 | KDM4E (0.48) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL20657365 | 0.86 | KDM4E (0.48) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL28461019 | 0.86 | KDM4E (0.48) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL28081071 | 0.75 | KDM4E (0.44) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL10325486 | 0.74 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL28919637 | 0.74 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL10344862 | 0.74 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL10325207 | 0.74 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL23133630 | 0.72 | KDM4E (0.47) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL18972932 | 0.72 | KDM4E (0.51) | KDM4ELMNACYP2D6CYP2C19HK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130231444-A1 | RESORBABLE PHENOLIC POLYMERS | TYRX PHARMA, INC. (US) | 2013-09-05 | — | — | US | disclosed |
| US-8471054-B2 | Resorbable phenolic polymers | TYRX, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20120165495-A1 | RESORBABLE PHENOLIC POLYMERS | TYRX, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| US-8153837-B2 | Resorbable phenolic polymers | TYRX, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090088548-A1 | Resorbable Phenolic Polymers | TYRX PHARMA, INC. (US) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165495-A1 | RESORBABLE PHENOLIC POLYMERS | PAH, PUF60, MKI67 | KDM4E 396/4885LMNA 3812/4885CYP2D6 459/4885 |
| US-20090088548-A1 | Resorbable Phenolic Polymers | PAH, PUF60, MKI67 | KDM4E 396/4885LMNA 3812/4885CYP2D6 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.