Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859099 | 1.00 | KMT2A (0.51) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10854674 | 0.89 | KMT2A (0.54) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10852732 | 0.87 | KMT2A (0.54) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10852735 | 0.87 | KMT2A (0.54) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10852940 | 0.87 | KMT2A (0.54) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10855160 | 0.84 | KMT2A (0.51) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10855165 | 0.84 | KMT2A (0.51) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10849598 | 0.78 | KMT2A (0.56) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10854000 | 0.78 | MEN1 (0.55) | KMT2AMEN1ALOX5RAB9ANPC1 | |
| SCHEMBL10855290 | 0.78 | MEN1 (0.55) | KMT2AMEN1ALOX5RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4579847-A | Amino derivatives of benzylidene-pyrrolo[2,1-b]quinazolines useful for treating conditions of allergic origin | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-04-01 | — | — | US | disclosed |