Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207274 | 1.00 | CAPN1 (0.53) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL10862139 | 1.00 | CAPN1 (0.53) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL8207267 | 1.00 | CAPN1 (0.53) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL8207257 | 1.00 | CAPN1 (0.53) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL10996256 | 0.93 | MAPK1 (0.48) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL10996264 | 0.93 | MAPK1 (0.48) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL10996271 | 0.93 | MAPK1 (0.48) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL10861490 | 0.90 | CAPN1 (0.56) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL10861495 | 0.90 | CAPN1 (0.56) | CAPN1MAPK1CHRM3LMNATSHR | |
| SCHEMBL10861504 | 0.90 | CAPN1 (0.56) | CAPN1MAPK1CHRM3LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596803-A | Treating myocardial infarction | NIPPON CHEMIPHAR CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4507297-A | MYOCARDIAL INFARCTION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-03-26 | — | — | US | disclosed |