Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94190 | 0.95 | — | — | |
| SCHEMBL6303961 | 0.91 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2THPO | |
| Water SCHEMBL29244009 | 0.91 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2THPO | |
| Ammonia Solution, Strong SCHEMBL28916441 | 0.91 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2THPO | |
| Ethylene Glycol SCHEMBL28591871 | 0.91 | TDP1 (0.50) | TDP1TSHRSMN1; SMN2THPO | |
| SCHEMBL5167230 | 0.84 | TDP1 (0.44) | TDP1TSHRSMN1; SMN2 | |
| SCHEMBL5171971 | 0.84 | TDP1 (0.44) | TDP1TSHRSMN1; SMN2 | |
| Methylene Chloride SCHEMBL28997220 | 0.84 | TDP1 (0.44) | TDP1TSHRSMN1; SMN2 | |
| SCHEMBL5169066 | 0.84 | TDP1 (0.44) | TDP1TSHRSMN1; SMN2 | |
| Thiodiglycol SCHEMBL10635723 | 0.84 | TDP1 (0.77) | TDP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877227-B2 | Hydrogel nanocomposites for intraocular lens applicatons | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2014-11-04 | — | — | US | disclosed |
| US-8192485-B2 | especially made of copolymer that can be a hydrogel when in an oxidized state and can be a solution when in a reduced state; intraocular lenses; vitreous substitutes; treating skin conditions | The United States of America, as represented by the Department of Veterens Affairs (US) | 2012-06-05 | — | — | US | disclosed |
| US-8153156-B2 | Hydrogel nanocompsites for ophthalmic applications | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (US) | 2012-04-10 | — | — | US | disclosed |
| US-20110144228-A1 | HYDROGEL NANOCOMPOSITES FOR INTRAOCULAR LENS APPLICATONS | WASHINGTON UNIVERSITY | 2011-06-16 | — | — | US | disclosed |
| US-20070269488-A1 | Hydrogel Nanocompsites for Ophthalmic Applications | THE WASHINGTON UNIVERSITY IN ST. LOUIS | 2007-11-22 | — | — | US | disclosed |
| EP-1660153-A2 | HYDROGEL NANOCOMPSITES FOR OPHTHALMIC APPLICATIONS | The United States of America as represented by the Department of Veterans Affairs (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005023331-A2 | HYDROGEL NANOCOMPSITES FOR OPHTHALMIC APPLICATIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2005-03-17 | — | — | WO | disclosed |
| US-20040156880-A1 | Reversible hydrogel systems and methods therefor | DEPARTMENT OF VETERANS AFFAIRS, THE | 2004-08-12 | — | — | US | disclosed |