SCHEMBL1086409

SCHEMBL1086409

CCCCCCCCCCCCCCCCCCc1cc(CCCCCCCCCCCCCCCCCC)c(O)c(C(C)(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.54
PTGS2 P35354 8/20 0.51
CYP3A4 P08684 2/20 0.49
ALOX5 P09917 4/20 0.45
GAA P10253 2/20 0.44
KMT2A Q03164 1/20 0.44
ESR1 P03372 2/20 0.43
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
TACR2 P21452 2/20 0.43
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
SHBG P04278 1/20 0.43
TP53 P04637 1/20 0.43
HSPD1 P10809 1/20 0.43
ADRB3 P13945 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8351586 1.00 HSPA5 (0.54) HSPA5PTGS2CYP3A4ALOX5GAA
SCHEMBL27524411 0.97 HSPA5 (0.51) HSPA5PTGS2CYP3A4ALOX5GAA
SCHEMBL8508296 0.97 HSPA5 (0.54) HSPA5PTGS2CYP3A4ALOX5GAA
SCHEMBL3687864 0.92 HSPA5 (0.66) HSPA5PTGS2CYP3A4GAAKMT2A
SCHEMBL8509844 0.92 HSPA5 (0.66) HSPA5PTGS2CYP3A4GAAKMT2A
SCHEMBL25424133 0.92 HSPA5 (0.57) HSPA5PTGS2CYP3A4GAAKMT2A
SCHEMBL3689390 0.92 HSPA5 (0.66) HSPA5PTGS2CYP3A4GAAKMT2A
SCHEMBL3812694 0.92 HSPA5 (0.66) HSPA5PTGS2CYP3A4GAAKMT2A
SCHEMBL3694426 0.92 HSPA5 (0.66) HSPA5PTGS2CYP3A4GAAKMT2A
SCHEMBL27480104 0.92 HSPA5 (0.47) HSPA5PTGS2CYP3A4ALOX5GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3180399-B1 TERPOLYMER COMPOSITIONS WITH IMPROVED CLARITY AND GLOSS EQUISTAR CHEM LP (US) 2026-01-14 EP disclosed
US-11015039-B2 Terpolymer compositions with improved clarity and gloss for blow molded and thermoformed articles EQUISTAR CHEMICALS, LP (US) 2021-05-25 US disclosed
EP-3180399-A1 TERPOLYMER COMPOSITIONS WITH IMPROVED CLARITY AND GLOSS Equistar Chemicals LP (US) 2017-06-21 EP disclosed
US-20160046787-A1 TERPOLYMER COMPOSITIONS WITH IMPROVED CLARITY AND GLOSS FOR BLOW MOLDED AND THERMOFORMED ARTICLES Basell Poliolefine Italia, s.r.l. (IT) 2016-02-18 US disclosed
WO-2016025326-A1 TERPOLYMER COMPOSITIONS WITH IMPROVED CLARITY AND GLOSS EQUISTAR CHEMICALS, LP (US) 2016-02-18 WO disclosed
EP-2173806-B1 USE OF NUCLEATED PROPYLENE BUTENE TERPOLYMERS FOR THE PRODUCTION OF STERILIZABLE BLOWN FILMS BOREALIS TECH OY (FI) 2012-10-10 EP disclosed
US-8153714-B2 Process for producing polyolefin molded articles comprising an ethylene-vinyl alcohol copolymer BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-04-10 US disclosed
EP-1960466-B1 A PROCESS FOR PRODUCING POLYOLEFIN MOLDED ARTICLES COMPRISING AN ETHYLENE-VINYL ALCOHOL COPOLYMER BASELL POLIOLEFINE SRL (IT) 2011-02-23 EP disclosed
US-20100266797-A1 Process for Producing Polyolefin Molded Articles Comprising an Ethylene-Vinyl Alcohol Copolymer BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2010-10-21 US disclosed
EP-2173806-A1 USE OF NUCLEATED PROPYLENE BUTENE TERPOLYMERS FOR THE PRODUCTION OF STERILIZABLE BLOWN FILMS Borealis Technology OY (FI) 2010-04-14 EP disclosed
EP-0878567-A2 Polyolefin fibres and polyolefin yarns and textile materials thereof PCD Polymere AG (AT) 1998-11-18 EP disclosed
EP-0546573-B1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC (US) 1998-03-11 EP disclosed
EP-0821018-A2 Crosslinkable olefinic polymers and method for their preparation PCD-Polymere Gesellschaft m.b.H. (AT) 1998-01-28 EP disclosed
EP-0817813-A1 POLYOLEFIN COMPOSITION SUITED FOR METAL COATING BY FLAME SPRAYING Montell North America Inc. (US) 1998-01-14 EP disclosed
EP-0792905-A2 Continuous process for preparing polypropylene compositions with improved stress crack resistance and high melt strength PCD-Polymere Gesellschaft m.b.H. (AT) 1997-09-03 EP disclosed
EP-0792894-A2 Continuous modification of polyolefins in solid phase PCD-Polymere Gesellschaft m.b.H. (AT) 1997-09-03 EP disclosed
WO-1997028213-A1 POLYOLEFIN COMPOSITION SUITED FOR METAL COATING BY FLAME SPRAYING MONTELL NORTH AMERICA INC. (IT) 1997-08-07 WO disclosed
EP-0787750-A2 Poly(alkylethylene) structural isomers PCD-Polymere Gesellschaft m.b.H. (AT) 1997-08-06 EP disclosed
US-5278210-A Process for the preparation of stabilized polyolefins and products obtained therefrom HIMONT INCORPORATED (US) 1994-01-11 US disclosed
EP-0546573-A1 Process for the preparation of stabilized polyolefins and products obtained therefrom MONTELL NORTH AMERICA INC. (US) 1993-06-16 EP disclosed