SCHEMBL10864191

SCHEMBL10864191

COC(=O)C(C)ON=C(N)N

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.38
CA12 O43570 2/20 0.33
F9 P00740 1/20 0.31
PLAU P00749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8971223 0.76
SCHEMBL8971234 0.71
SCHEMBL22356006 0.71 CA14 (0.43) CA14SMN1; SMN2CA12F9PLAU
SCHEMBL22356151 0.71 CA14 (0.43) CA14SMN1; SMN2CA12F9PLAU
SCHEMBL14783842 0.71 CA14 (0.43) CA14SMN1; SMN2CA12F9PLAU
SCHEMBL8549706 0.70
SCHEMBL20397638 0.70
SCHEMBL7277124 0.70
SCHEMBL31030153 0.70
SCHEMBL4633092 0.69 SMN1; SMN2 (0.48) CA14SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0203220-A1 Benzolactamsultams BAYER AG (DE) 1986-12-03 EP disclosed