SCHEMBL1086477

SCHEMBL1086477

C#CC[Si](C)(C)C[Si](C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21924510 0.81
SCHEMBL4320494 0.74
SCHEMBL17858 0.74
SCHEMBL4317358 0.73
SCHEMBL12375242 0.69
SCHEMBL10635887 0.65
SCHEMBL2761275 0.65 SMN1; SMN2 (0.30)
SCHEMBL698327 0.65
SCHEMBL3485850 0.65
SCHEMBL10864985 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070255014-A1 Gas-permeable materials and medical devices SOLTA MEDICAL, INC. 2007-11-01 US claimed
US-8153726-B2 Highly oxygen permeable rigid contact lenses from polyacetylenes THE LAGADO CORPORATION (US) 2012-04-10 US disclosed
WO-2007041166-A2 HIGHLY OXYGEN PERMEABLE RIGID CONTACT LENSES FROM POLYACETYLENES THE LAGADO CORPORATION (US) 2007-04-12 WO disclosed
US-20070078245-A1 Highly Oxygen Permeable Rigid Contact Lenses from Polyacetylenes THE LAGADO CORPORATION (US) 2007-04-05 US disclosed
EP-0237581-B1 POLY(DI-SUBSTITUTED ACETYLENE)/POLYORGANOSILOXANE GRAFT COPOLYMER AND GAS SEPARATION MEMBRANE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-12-27 EP disclosed
EP-0408334-A2 Silicon-containing resists and microlithography using same FUJITSU LIMITED (JP) 1991-01-16 EP disclosed
US-4755561-A Poly(disubstituted acetylene)/polyorganosiloxane graft copolymer and membrane for gas separation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-07-05 US disclosed
US-4746334-A OXYGEN SEPARATORS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1988-05-24 US disclosed
EP-0237581-A1 POLY(DI-SUBSTITUTED ACETYLENE)/POLYORGANOSILOXANE GRAFT COPOLYMER AND GAS SEPARATION MEMBRANE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-09-23 EP disclosed