Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.84 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.84 |
| ▸ | USP2 | O75604 | 5/20 | 0.84 |
| ▸ | PGR | P06401 | 5/20 | 0.84 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.84 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.84 |
| ▸ | AR | P10275 | 2/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.84 |
| ▸ | CNR1 | P21554 | 1/20 | 0.84 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10354244 | 0.99 | CYP3A4 (0.83) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL10354280 | 0.99 | CYP3A4 (0.83) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL10354242 | 0.99 | CYP3A4 (0.83) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL10354243 | 0.99 | CYP3A4 (0.83) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL10354282 | 0.99 | CYP3A4 (0.83) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL10354278 | 0.99 | CYP3A4 (0.83) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL10354273 | 0.97 | CYP3A4 (0.87) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL10354274 | 0.97 | CYP3A4 (0.87) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL11430009 | 0.94 | CYP3A4 (0.76) | CYP3A4NR3C1USP2PGRADORA3 | |
| SCHEMBL11423737 | 0.94 | CYP3A4 (0.77) | CYP3A4NR3C1USP2PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170500-A2 | Novel 9 alpha-fluoro- or chloro-corticosteroid esters and a process for their preparation | HOVIONE INTER LTD. (CH) | 1986-02-05 | — | — | EP | claimed |