Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | PPOX | P50336 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867838 | 0.93 | MEN1 (0.56) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL8694365 | 0.85 | TDP1 (0.74) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL28236153 | 0.78 | CYP1A2 (0.42) | TDP1MAPTKDM4ECYP2C9CYP2C19 | |
| SCHEMBL10706908 | 0.78 | TDP1 (0.74) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10594849 | 0.77 | MEN1 (0.70) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10540835 | 0.77 | TDP1 (0.73) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL30689708 | 0.77 | TDP1 (0.73) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10931184 | 0.76 | TDP1 (0.71) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11168713 | 0.76 | TDP1 (0.68) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10948668 | 0.76 | TDP1 (0.71) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178708-A2 | Heteroaromatic ether herbicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-04-23 | — | — | EP | disclosed |