Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.96 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.96 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.96 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.96 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.96 |
| ▸ | LMNA | P02545 | 2/20 | 0.96 |
| ▸ | DRD3 | P35462 | 1/20 | 0.96 |
| ▸ | XDH | P47989 | 1/20 | 0.96 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.53 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.53 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL3413249 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL3416956 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL29355156 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL29982697 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL29442902 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL29466915 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL8111 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL1331751 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL3414606 | 0.98 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| Adenine SCHEMBL11156033 | 0.96 | PI4KA (0.96) | PI4KAPI4K2BPI4K2API4KBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191624-A2 | Gold-purine antitumor agents | ENGELHARD CORPORATION (US) | 1986-08-20 | — | — | EP | disclosed |