Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10869600 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL9131797 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL10871122 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL10870763 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL10873955 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL10870853 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL10870786 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL10870982 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL10870865 | 1.00 | SIRT2 (0.39) | SIRT2TSHRTHRB | |
| SCHEMBL12586891 | 0.95 | TSHR (0.42) | SIRT2TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186083-A2 | N-(2-Hyxdroxyalkyl)-amino acids and their derivatives, process for their preparation and pharmaceutical compositions containing them | ASTA Pharma AG (DE) | 1986-07-02 | — | — | EP | disclosed |