Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871268 | 1.00 | ACE2 (0.53) | ACE2BLMLTA4HGABRR1CYP1A2 | |
| SCHEMBL10870027 | 1.00 | ACE2 (0.53) | ACE2BLMLTA4HGABRR1CYP1A2 | |
| SCHEMBL10869079 | 1.00 | ACE2 (0.53) | ACE2BLMLTA4HGABRR1CYP1A2 | |
| SCHEMBL1427872 | 1.00 | ACE2 (0.53) | ACE2BLMLTA4HGABRR1CYP1A2 | |
| SCHEMBL28544692 | 1.00 | ACE2 (0.53) | ACE2BLMLTA4HGABRR1CYP1A2 | |
| SCHEMBL1132439 | 0.98 | BLM (0.54) | ACE2BLMLTA4HGABRR1CYP1A2 | |
| SCHEMBL1132028 | 0.91 | — | — | |
| SCHEMBL5977939 | 0.88 | ACE2 (0.64) | ACE2BLMLTA4HGABRR1CYP1A2 | |
| SCHEMBL20612872 | 0.88 | ACE2 (0.64) | ACE2BLMLTA4HGABRR1CYP1A2 | |
| SCHEMBL9001608 | 0.88 | ACE2 (0.64) | ACE2BLMLTA4HGABRR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186083-A2 | N-(2-Hyxdroxyalkyl)-amino acids and their derivatives, process for their preparation and pharmaceutical compositions containing them | ASTA Pharma AG (DE) | 1986-07-02 | — | — | EP | disclosed |