SCHEMBL1087200

SCHEMBL1087200

[C-]#[N+]c1c(C(=O)OCC)nsc1/N=N/c1c(O)c(C(=O)Nc2ccc(C)cc2)cc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
NQO2 P16083 1/20 0.42
MEN1 O00255 9/20 0.40
KMT2A Q03164 9/20 0.40
POLB P06746 4/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
MAOA P21397 1/20 0.38
AHR P35869 1/20 0.37
MAPT P10636 2/20 0.36
ELANE P08246 1/20 0.36
MAPK1 P28482 1/20 0.36
APOBEC3A P31941 1/20 0.36
APOBEC3G Q9HC16 1/20 0.36
CYP3A4 P08684 2/20 0.35
GAA P10253 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16330266 0.86 SMN1; SMN2 (0.42) SMN1; SMN2TP53NQO2MEN1KMT2A
SCHEMBL11885417 0.86 NQO2 (0.43) SMN1; SMN2NQO2MEN1KMT2APOLB
SCHEMBL1087346 0.82 NQO2 (0.55) SMN1; SMN2NQO2MEN1KMT2APOLB
SCHEMBL1087271 0.81 NQO2 (0.46) SMN1; SMN2NQO2MEN1KMT2APOLB
SCHEMBL15031136 0.77 NQO2 (0.43) SMN1; SMN2NQO2MEN1KMT2APOLB
SCHEMBL1087413 0.72 F10 (0.41) SMN1; SMN2TP53NQO2MEN1KMT2A
SCHEMBL13863125 0.72 NQO2 (0.73) SMN1; SMN2TP53NQO2MEN1KMT2A
SCHEMBL1084912 0.72 NQO2 (0.58) SMN1; SMN2NQO2MEN1KMT2APOLB
SCHEMBL14460161 0.71 NQO2 (0.60) SMN1; SMN2TP53NQO2MEN1KMT2A
SCHEMBL14460164 0.71 NQO2 (0.55) SMN1; SMN2TP53NQO2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8152863-B2 Pigment dispersion composition, red colored composition, colored curable composition, color filter for a solid state imaging device and method for producing the same, and solid state imaging device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20110294050-A1 PIGMENT DISPERSION COMPOSITION, RED COLORED COMPOSITION, COLORED CURABLE COMPOSITION, COLOR FILTER FOR A SOLID STATE IMAGING DEVICE AND METHOD FOR PRODUCING THE SAME, AND SOLID STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-12-01 US disclosed