SCHEMBL10872009

SCHEMBL10872009

COSSc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
MAPT P10636 2/20 0.55
MGLL Q99685 1/20 0.55
HSD17B10 Q99714 1/20 0.55
CA4 P22748 2/20 0.38
ALDH1A1 P00352 5/20 0.36
MAPK1 P28482 2/20 0.36
KCNH2 Q12809 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
LTA4H P09960 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7759264 0.73 HPGD (1.00) HPGDSMN1; SMN2MAPTMGLLHSD17B10
Benzene SCHEMBL27891544 0.73 HPGD (1.00) HPGDSMN1; SMN2MAPTMGLLHSD17B10
SCHEMBL5148 0.73 HPGD (1.00) HPGDSMN1; SMN2MAPTMGLLHSD17B10
SCHEMBL5695276 0.72
SCHEMBL9018822 0.70 CA4 (0.59) HPGDSMN1; SMN2MAPTMGLLHSD17B10
SCHEMBL30656885 0.70 HPGD (0.92) HPGDSMN1; SMN2MAPTMGLLHSD17B10
Hydrochloric Acid SCHEMBL8855667 0.70 HPGD (0.92) HPGDSMN1; SMN2MAPTMGLLHSD17B10
Fluoride SCHEMBL28586370 0.70 HPGD (0.92) HPGDSMN1; SMN2MAPTMGLLHSD17B10
SCHEMBL28643321 0.70 HPGD (0.92) HPGDSMN1; SMN2MAPTMGLLHSD17B10
Ammonia Solution, Strong SCHEMBL14937632 0.70 HPGD (0.92) HPGDSMN1; SMN2MAPTMGLLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0194793-A2 9-Acyl tylosin derivatives Omura, Satoshi (JP) 1986-09-17 EP disclosed
US-4594338-A Bactericide OMURA SATOSHI (JP) 1986-06-10 US disclosed
EP-0154495-A2 Improvements in or relating to thioether macrolide derivatives Omura, Satoshi (JP) 1985-09-11 EP disclosed