Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | EEF2K | O00418 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | MATK | P42679 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL12275781 | 0.97 | AURKB (0.46) | AURKBAURKACASP6KCNJ11CDC7 | |
| Water SCHEMBL12275782 | 0.83 | NR4A1 (0.46) | AURKBAURKACASP6KCNJ11ALDH1A1 | |
| SCHEMBL5720558 | 0.82 | KDM4E (0.45) | AURKBAURKACDC7EEF2KPLK4 | |
| SCHEMBL7894762 | 0.79 | AURKB (0.56) | AURKBAURKACASP6CDC7EEF2K | |
| SCHEMBL9765207 | 0.76 | AURKB (0.52) | AURKBAURKACASP6CDC7EEF2K | |
| SCHEMBL8003311 | 0.76 | AURKB (0.58) | AURKBAURKACASP6CDC7EEF2K | |
| SCHEMBL11133668 | 0.74 | KCNJ11 (0.46) | AURKBAURKACASP6KCNJ11ALDH1A1 | |
| SCHEMBL29608931 | 0.73 | AURKB (0.64) | AURKBAURKACDC7EEF2KPLK4 | |
| SCHEMBL156055 | 0.73 | AURKB (0.64) | AURKBAURKACDC7EEF2KPLK4 | |
| SCHEMBL156054 | 0.73 | AURKB (0.55) | AURKBAURKACASP6CDC7EEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394445-B2 | Method for continuously preparing water-soluble azo dye by coupling a nebulizer with a pipeline | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2016-07-19 | — | — | US | disclosed |
| US-20150073132-A1 | METHOD FOR CONTINUOUSLY PREPARING WATER-SOLUBLE AZO DYE BY COUPLING A NEBULIZER WITH A PIPELINE | DALIAN UNIVERSITY OF TECHNOLOGY (CN) | 2015-03-12 | — | — | US | disclosed |
| EP-0122881-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-08-13 | — | — | EP | disclosed |
| US-4545785-A | FIBER-REACTIVE DYES FOR CELLULOSE | CIBA-GEIGY CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| EP-0122881-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-10-24 | — | — | EP | disclosed |