Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10828542 | 0.87 | NR1I2 (0.65) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10828551 | 0.87 | NR1I2 (0.65) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10420015 | 0.86 | NR1I2 (0.59) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10420013 | 0.86 | NR1I2 (0.59) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10646353 | 0.85 | TDP1 (0.45) | NR1I2PGRTDP1MAPTALDH1A1 | |
| SCHEMBL10646349 | 0.85 | TDP1 (0.45) | NR1I2PGRTDP1MAPTALDH1A1 | |
| SCHEMBL10647494 | 0.84 | TDP1 (0.44) | NR1I2PGRTDP1MAPTALDH1A1 | |
| SCHEMBL10647490 | 0.84 | TDP1 (0.44) | NR1I2PGRTDP1MAPTALDH1A1 | |
| SCHEMBL10466826 | 0.82 | NR1I2 (0.47) | NR1I2PGRPTGS2TDP1MAPT | |
| SCHEMBL10466825 | 0.82 | NR1I2 (0.47) | NR1I2PGRPTGS2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191507-A2 | New 2-oxyimino-3-oxobutyric acid derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |