SCHEMBL1087447

SCHEMBL1087447

COc1ccc(NC(=O)c2cc3ccccc3c(/N=N/c3nncn3-c3nc4ccccc4s3)c2O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.46
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
RAB9A P51151 5/20 0.46
MAPT P10636 2/20 0.46
ALDH1A1 P00352 1/20 0.46
PKM P14618 1/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP3A4 P08684 5/20 0.43
DUSP3 P51452 1/20 0.43
GPX4 P36969 1/20 0.43
CASP3 P42574 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
CTSD P07339 1/20 0.41
NQO2 P16083 1/20 0.41
AHR P35869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1086766 0.89 NQO2 (0.41) NPC1MEN1KMT2AMAPTALDH1A1
SCHEMBL1085865 0.78 MEN1 (0.52) NPC1MEN1KMT2ARAB9AMAPT
SCHEMBL1086018 0.76 NPC1 (0.51) NPC1MEN1KMT2ARAB9AMAPT
SCHEMBL28117090 0.75 NQO2 (0.65) NPC1MEN1KMT2ARAB9AMAPT
SCHEMBL20862127 0.75 NQO2 (0.65) NPC1MEN1KMT2ARAB9AMAPT
SCHEMBL11886522 0.74 CYP3A4 (0.48) NPC1MEN1KMT2ARAB9AMAPT
SCHEMBL20886079 0.73 NQO2 (0.60) NPC1MEN1KMT2ARAB9AMAPT
SCHEMBL1087708 0.73 NPC1 (0.52) NPC1MEN1KMT2ARAB9AMAPT
SCHEMBL10265336 0.73 NPC1 (0.52) NPC1MEN1KMT2ARAB9AMAPT
SCHEMBL1087149 0.72 MAPT (0.49) NPC1MEN1KMT2ARAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465553-B2 Pigment dispersion composition, colored curable composition, color filter for solid-state image sensor and method of producing the same, and solid-state image sensor FUJIFILM CORPORATION (JP) 2013-06-18 US disclosed
US-20120286145-A1 PIGMENT DISPERSION COMPOSITION, COLORED CURABLE COMPOSITION, COLOR FILTER FOR SOLID-STATE IMAGE SENSOR AND METHOD OF PRODUCING THE SAME, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2012-11-15 US disclosed
US-8226734-B2 Azo compound, azo pigment, pigment dispersion, coloring composition, ink for inkjet recording, coloring composition for color filter, color filter, and process for preparing a coloring composition for color filter FUJIFILM CORPORATION (JP) 2012-07-24 US disclosed
US-8152863-B2 Pigment dispersion composition, red colored composition, colored curable composition, color filter for a solid state imaging device and method for producing the same, and solid state imaging device FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20110294050-A1 PIGMENT DISPERSION COMPOSITION, RED COLORED COMPOSITION, COLORED CURABLE COMPOSITION, COLOR FILTER FOR A SOLID STATE IMAGING DEVICE AND METHOD FOR PRODUCING THE SAME, AND SOLID STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-12-01 US disclosed
US-20110143270-A1 AZO COMPOUND, AZO PIGMENT, PIGMENT DISPERSION, COLORING COMPOSITION, INK FOR INKJET RECORDING, COLORING COMPOSITION FOR COLOR FILTER, COLOR FILTER, AND PROCESS FOR PREPARING A COLORING COMPOSITION FOR COLOR FILTER FUJIFILM CORPORATION (JP) 2011-06-16 US disclosed