Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | PPOX | P50336 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943534 | 0.93 | MEN1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10949055 | 0.88 | TDP1 (0.60) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10948291 | 0.88 | TDP1 (0.60) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10949685 | 0.85 | MEN1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10873581 | 0.85 | MEN1 (0.51) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10948614 | 0.84 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10950904 | 0.84 | MEN1 (0.53) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10875493 | 0.84 | MEN1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10875495 | 0.84 | MEN1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10944416 | 0.84 | TDP1 (0.56) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177591-A1 | NOVEL PHOSPHINATES | SANDOZ AG (CH) | 1986-04-16 | — | — | EP | disclosed |
| WO-1985004661-A1 | NOVEL PHOSPHINATES | SANDOZ AG (CH) | 1985-10-24 | — | — | WO | disclosed |