Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | DRD4 | P21917 | 5/20 | 0.53 |
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873091 | 0.90 | SMN1; SMN2 (0.49) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL10869866 | 0.80 | HTR2A (0.51) | DRD2DRD3MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL10870609 | 0.79 | HTR2A (0.50) | DRD2DRD3MEN1KMT2AALDH1A1 | |
| SCHEMBL10873341 | 0.76 | HTR2A (0.54) | DRD2DRD3KMT2AALDH1A1LMNA | |
| SCHEMBL24588680 | 0.73 | CYP2D6 (0.69) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL29743918 | 0.73 | CYP2D6 (0.69) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL10871125 | 0.71 | SMN1; SMN2 (0.51) | DRD2DRD4DRD3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10867337 | 0.71 | SMN1; SMN2 (0.47) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL10866946 | 0.71 | SMN1; SMN2 (0.47) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL10867780 | 0.70 | KMT2A (0.50) | DRD2DRD4DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187619-A2 | 1,3-Disubstituted tetrahydropyridines | CIBA-GEIGY AG (CH) | 1986-07-16 | — | — | EP | disclosed |