SCHEMBL10876110

SCHEMBL10876110

CO[Si](CCCCOC[C@@H]1CO1)(OC)OC

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.64
ALDH1A1 P00352 4/20 0.58
TDP1 Q9NUW8 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.56
MAPK1 P28482 1/20 0.40
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23497528 1.00 TSHR (0.64) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL187566 1.00 TSHR (0.64) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL6048411 0.98 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23706413 0.98 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL18191930 0.98 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23149852 0.98 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23706442 0.98 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23149854 0.98 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL23706446 0.98 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL3127469 0.98 TSHR (0.62) TSHRALDH1A1TDP1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240069441-A1 COMPOSITION FOR RESIST UNDERLYING FILM FORMATION NISSAN CHEMICAL CORPORATION (JP) 2024-02-29 US disclosed
EP-0203730-A2 Anti-reflection optical article and process for preparation thereof TORAY INDUSTRIES, INC. (JP) 1986-12-03 EP disclosed