Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 2/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398737 | 1.00 | PTPN11 (0.51) | PTPN11PTPN1PTPN6RARBTSHR | |
| SCHEMBL9398800 | 0.89 | PTPN11 (0.49) | PTPN11PTPN1PTPN6MEN1ALDH1A1 | |
| SCHEMBL17485630 | 0.84 | CYP2D6 (0.53) | PTPN11PTPN1PTPN6RARBTSHR | |
| SCHEMBL2208315 | 0.84 | PTPN11 (0.55) | PTPN11PTPN1PTPN6S1PR2S1PR1 | |
| SCHEMBL9399352 | 0.84 | RARB (0.55) | PTPN11PTPN1PTPN6RARBTSHR | |
| SCHEMBL28509682 | 0.83 | S1PR2 (0.55) | S1PR2S1PR1S1PR3LPAR2MEN1 | |
| SCHEMBL10980962 | 0.82 | SMN1; SMN2 (0.59) | PTPN11PTPN1PTPN6RARBTSHR | |
| SCHEMBL10877899 | 0.82 | CYP1A2 (0.49) | PTPN11PTPN1PTPN6RARBTSHR | |
| SCHEMBL9398849 | 0.82 | RARB (0.57) | PTPN11PTPN1PTPN6RARBTSHR | |
| SCHEMBL9399532 | 0.82 | PTPN11 (0.45) | PTPN11PTPN1PTPN6RARBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087056-B1 | BENZONITRILES | MERCK PATENT GmbH (DE) | 1986-01-15 | — | — | EP | disclosed |