Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.48 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.48 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878394 | 1.00 | NR1I2 (0.48) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10867766 | 0.92 | NR1I2 (0.41) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10867773 | 0.92 | NR1I2 (0.41) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10747368 | 0.89 | NR1I2 (0.46) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10951819 | 0.88 | NR1I2 (0.48) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11247274 | 0.85 | NR1I2 (0.47) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10528959 | 0.83 | NR1I2 (0.56) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| Iodide SCHEMBL10695908 | 0.81 | KMT2A (0.55) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10878866 | 0.81 | NR1I2 (0.55) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10878869 | 0.81 | NR1I2 (0.55) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0176369-A2 | 7-(Alpha-(4-oxo-2-azetidinyl(or -azetidinylalkyl)-oxyimino)-alpha-(2-amino-4-thiazolyl)acetamido]-3- substituted-Delta 3-cephem-4-carboxylic acid compounds and salts thereof, their production, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-04-02 | — | — | EP | disclosed |