SCHEMBL1087994

SCHEMBL1087994

CCCCCCCCCCCCCCCCOC[C@H](COC1OC(CO)C(O)C(O)C1O)NC(=O)NC

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SELE P16581 5/20 0.51
SELL P14151 3/20 0.51
SELP P16109 3/20 0.51
MAPK1 P28482 1/20 0.48
CETP P11597 1/20 0.46
APP P05067 1/20 0.43
PLA2G2C Q5R387 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1087728 0.84 PLA2G2C (0.47) SELESELLSELPMAPK1PLA2G2C
SCHEMBL19079115 0.80 MAPK1 (0.47) SELESELLSELPMAPK1CETP
SCHEMBL19079114 0.79 MAPK1 (0.46) SELESELLSELPMAPK1PLA2G2C
SCHEMBL9019252 0.79 CETP (0.56) SELESELLSELPMAPK1CETP
SCHEMBL9019200 0.79 CETP (0.56) SELESELLSELPMAPK1CETP
SCHEMBL9019182 0.79 CETP (0.56) SELESELLSELPMAPK1CETP
SCHEMBL9019248 0.79 CETP (0.56) SELESELLSELPMAPK1CETP
SCHEMBL9019195 0.79 CETP (0.56) SELESELLSELPMAPK1CETP
SCHEMBL9019272 0.79 CETP (0.56) SELESELLSELPMAPK1CETP
SCHEMBL9019250 0.79 CETP (0.56) SELESELLSELPMAPK1CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153615-B2 Synthesis of glycerolipid carbamates and dicarbamates and their use as an antitumor compounds THE UNIVERSITY OF MANITOBA (CA) 2012-04-10 US disclosed
US-20090042811-A1 Synthesis of Glycerolipid Carbamates and Dicarbamates and Their Use as an Antitumor Compounds THE UNIVERSITY OF MANITOBA (CA) 2009-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042811-A1 Synthesis of Glycerolipid Carbamates and Dicarbamates and Their Use as an Antitumor Compounds PHOSPHO1, SGMS1, UGCG SELE 4116/4885SELL 4124/4885SELP 3610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.