SCHEMBL1088097

SCHEMBL1088097

C=CC(=O)OC(Cl)/C=C/C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.36
HPGD P15428 1/20 0.31
ALDH1A1 P00352 3/20 0.30
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30
CYP3A4 P08684 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1088099 1.00 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8446696 0.78 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2746486 0.78
SCHEMBL7871430 0.77 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL7871432 0.77 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL11507613 0.74
SCHEMBL11507618 0.74
SCHEMBL10769092 0.73
SCHEMBL393935 0.73
SCHEMBL3179256 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140296404-A1 CROSSLINKABLE RUBBER COMPOSITION AND CROSS-LINKED RUBBER ZEON CORP (JP) 2014-10-02 US disclosed
US-8785530-B2 Crosslinkable rubber composition and cross-linked rubber ZEON CORPORATION (JP) 2014-07-22 US disclosed
US-20130102725-A1 CROSSLINKABLE RUBBER COMPOSITION AND CROSS-LINKED RUBBER ZEON CORPORATION (JP) 2013-04-25 US disclosed
US-8362121-B2 Crosslinkable rubber composition and cross-linked rubber ZEON CORPORATION (JP) 2013-01-29 US disclosed
EP-1964882-B1 CROSSLINKABLE RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORP (JP) 2012-07-18 EP disclosed
US-20120172509-A1 CROSSLINKABLE RUBBER COMPOSITION AND CROSS-LINKED RUBBER NAGAMORI HIROYASU (JP) 2012-07-05 US disclosed
US-8153712-B2 Crosslinkable rubber composition and cross-linked rubber ZEON CORPORATION (JP) 2012-04-10 US disclosed
US-20100168302-A1 Crosslinkable Rubber Composition and Cross-Linked Rubber ZEON CORPORATION (JP) 2010-07-01 US disclosed
EP-1964882-A1 CROSSLINKABLE RUBBER COMPOSITION AND RUBBER CROSSLINKED PRODUCT ZEON CORPORATION (JP) 2008-09-03 EP disclosed
EP-1234851-B1 CROSSLINKABLE RUBBER COMPOSITION AND CROSSLINKED OBJECT ZEON CORP (JP) 2004-05-19 EP disclosed
EP-1234851-A1 CROSSLINKABLE RUBBER COMPOSITION AND CROSSLINKED OBJECT Zeon Corporation (JP) 2002-08-28 EP disclosed
EP-0538640-B1 Acrylic copolymer elastomer and vulcanizable composition containing same NIPPON ZEON CO (JP) 1996-09-04 EP disclosed
US-5334683-A Low temperature resistance, oil resistance NIPPON ZEON CO., LTD. (JP) 1994-08-02 US disclosed
US-5280080-A Copolymerizing mixture of alkyl acrylates NIPPON ZEON CO., LTD. (JP) 1994-01-18 US disclosed
US-5216101-A Heat, cold, ozone and oil resistance; useful for gaskets, hoses, conveyor belts, packing and bearing or oil seals NIPPON ZEON CO., LTD. (JP) 1993-06-01 US disclosed
EP-0538640-A1 Acrylic copolymer elastomer and vulcanizable composition containing same NIPPON ZEON CO., LTD. (JP) 1993-04-28 EP disclosed