Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | GBA1 | P04062 | 12/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.43 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.43 |
| ▸ | GJB2 | P29033 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881696 | 1.00 | MAPK1 (0.66) | MAPK1GBA1CA1CA2CA9 | |
| SCHEMBL10882040 | 0.95 | MAPK1 (0.62) | MAPK1GBA1CA1CA2CA9 | |
| SCHEMBL10882036 | 0.95 | MAPK1 (0.62) | MAPK1GBA1CA1CA2CA9 | |
| SCHEMBL10883601 | 0.90 | MAPK1 (0.56) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL10880043 | 0.90 | MAPK1 (0.56) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL10880031 | 0.90 | MAPK1 (0.56) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL9231776 | 0.86 | GBA1 (0.54) | MAPK1GBA1CA1CA2CA9 | |
| SCHEMBL9231772 | 0.86 | GBA1 (0.54) | MAPK1GBA1CA1CA2CA9 | |
| SCHEMBL29176364 | 0.86 | MAPK1 (0.69) | MAPK1GBA1CA1CA2CA9 | |
| SCHEMBL26624841 | 0.84 | MAPK1 (0.73) | MAPK1GBA1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593090-A | Containing perhydrofuran or pyran ring structure | GOGO KIMURA (JP) | 1986-06-03 | — | — | US | disclosed |
| EP-0067019-B1 | NOVEL NITROSOUREA COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Kimura, Goro (JP) | 1986-03-19 | — | — | EP | disclosed |
| EP-0067019-A1 | Novel nitrosourea compound, method for preparing same, and pharmaceutical composition containing same | Kimura, Goro (JP) | 1982-12-15 | — | — | EP | disclosed |