Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL1872106 | 0.95 | TSHR (0.60) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| Butane SCHEMBL8909318 | 0.86 | TSHR (0.72) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| Methyl Alcohol SCHEMBL9860225 | 0.86 | TSHR (0.81) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| Hydrogen Peroxide SCHEMBL30110573 | 0.83 | TSHR (0.87) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| Hydrogen Peroxide SCHEMBL298462 | 0.83 | TSHR (0.87) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL385555 | 0.83 | TSHR (1.00) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL8355 | 0.83 | TSHR (1.00) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL11645158 | 0.83 | TSHR (1.00) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL11606739 | 0.83 | TSHR (1.00) | TSHRHPGDL3MBTL1BCL2L1BAD | |
| SCHEMBL29358070 | 0.83 | TSHR (1.00) | TSHRHPGDL3MBTL1BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264806-B | Method for preparing tetrahydronaphthalene, cis-decalin and trans-decalin by naphthalene hydrogenation | 山东联成化学工业有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-113264806-A | Method for preparing tetrahydronaphthalene, cis-decalin and trans-decalin by naphthalene hydrogenation | 山东联成化学工业有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-1468235-A | Aminoheterocyclylamides as pesticides and antiparasitic agents | ��˹��ŵ�� | 2004-01-14 | — | — | CN | disclosed |
| CN-1384832-A | Pesticidal aminoheterocyclamide compounds | NOVARTIS AG (CH) | 2002-12-11 | — | — | CN | disclosed |
| CN-1384826-A | Pesticidal N-heteroaryl alpha-alkoximino-carboxamides | NOVARITS AG (CH) | 2002-12-11 | — | — | CN | disclosed |
| CN-1151737-A | 1, 2, 4, 6-thiatriazines with herbicidal activity | CIBA GEIGY AG (CH) | 1997-06-11 | — | — | CN | disclosed |
| EP-0089207-B1 | FRIEDEL-CRAFT REACTIONS | BUSH BOAKE ALLEN Limited (GB) | 1986-09-10 | — | — | EP | disclosed |
| US-4515990-A | Preparation of indanes, tetralins and phenyl alcohol in Friedel Craft reaction | BUSH BOAKE ALLEN LIMITED (GB) | 1985-05-07 | — | — | US | disclosed |
| EP-0104195-A1 | FRIEDEL CRAFT REACTIONS | BUSH BOAKE ALLEN Limited (GB) | 1984-04-04 | — | — | EP | disclosed |
| WO-1983003247-A1 | FRIEDEL CRAFT REACTIONS | FERBER, GERALD, JOHN | 1983-09-29 | — | — | WO | disclosed |
| EP-0089207-A1 | Friedel-Craft reactions | BUSH BOAKE ALLEN Limited (GB) | 1983-09-21 | — | — | EP | disclosed |