Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.96 |
| ▸ | HPGD | P15428 | 3/20 | 0.96 |
| ▸ | MAPT | P10636 | 2/20 | 0.96 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.96 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.96 |
| ▸ | MEN1 | O00255 | 1/20 | 0.96 |
| ▸ | TP53 | P04637 | 1/20 | 0.96 |
| ▸ | MTOR | P42345 | 1/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889456 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10883574 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10884118 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10547186 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10546382 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10886835 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10886839 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10883567 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10547191 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 | |
| SCHEMBL10546388 | 1.00 | TRPV1 (0.96) | TRPV1HPGDMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132346-B1 | NOVEL COMPOUNDS AND COMPOSITIONS USEFUL FOR PRODUCING ANALGESIA | THE PROCTER & GAMBLE COMPANY (US) | 1986-09-24 | — | — | EP | claimed |
| US-4544669-A | ALKADIENAMIDES | THE PROCTER & GAMBLE COMPANY (US) | 1985-10-01 | — | — | US | claimed |
| EP-0132346-A1 | Novel compounds and compositions useful for producing analgesia | THE PROCTER & GAMBLE COMPANY (US) | 1985-01-30 | — | — | EP | claimed |
| EP-0132346-B1 | NOVEL COMPOUNDS AND COMPOSITIONS USEFUL FOR PRODUCING ANALGESIA | THE PROCTER & GAMBLE COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4544669-A | ALKADIENAMIDES | THE PROCTER & GAMBLE COMPANY (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0132346-A1 | Novel compounds and compositions useful for producing analgesia | THE PROCTER & GAMBLE COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |