Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564181 | 1.00 | MAPT (0.57) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL3609468 | 0.88 | MAPT (0.58) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL3609471 | 0.88 | MAPT (0.58) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL321922 | 0.86 | MAPT (0.57) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL7030290 | 0.86 | KMT2A (0.76) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL12035802 | 0.86 | KMT2A (0.57) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL14358911 | 0.86 | MAPT (0.57) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL5617201 | 0.86 | KMT2A (0.57) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL7651650 | 0.86 | KMT2A (0.76) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL321923 | 0.86 | MAPT (0.57) | MAPTMEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107618-B1 | N-SUBSTITUTED-2-(1-IMIDAZOLYL)-INDOLES | CIBA-GEIGY AG (CH) | 1986-07-16 | — | — | EP | disclosed |
| US-4539410-A | THROMBOXANE SYNEHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1985-09-03 | — | — | US | disclosed |
| US-4511573-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| US-4478842-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| EP-0107618-A1 | N-substituted-2-(1-imidazolyl)-indoles | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |