Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 6/20 | 0.41 |
| ▸ | CPA1 | P15085 | 3/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HCK | P08631 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889174 | 1.00 | MME (0.44) | MMEFOLH1NPC1RAB9AACE | |
| SCHEMBL838650 | 0.87 | NPC1 (0.54) | MMEFOLH1NPC1RAB9AACE | |
| SCHEMBL838649 | 0.87 | NPC1 (0.54) | MMEFOLH1NPC1RAB9AACE | |
| SCHEMBL7263049 | 0.86 | MME (0.52) | MMEFOLH1NPC1RAB9AACE | |
| SCHEMBL10934250 | 0.83 | FOLH1 (0.51) | MMEFOLH1ACECPA1ACE2 | |
| SCHEMBL10934246 | 0.83 | FOLH1 (0.51) | MMEFOLH1ACECPA1ACE2 | |
| Tyrosine SCHEMBL608841 | 0.81 | SLC7A5 (0.58) | NPC1RAB9ARECQL | |
| Tyrosine SCHEMBL608840 | 0.81 | SLC7A5 (0.58) | NPC1RAB9ARECQL | |
| SCHEMBL6439790 | 0.76 | EPHX2 (0.56) | MMEACECPA1ACE2ALDH1A1 | |
| SCHEMBL29069408 | 0.76 | EPHX2 (0.56) | MMEACECPA1ACE2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4568636-A | QUANTITATIVE ANALYSIS OF PROTEOLYTIC ENZYMES, FLUORESCENCE; COLORIMETRIC ANALYSIS | PENTAPHARM AG (CH) | 1986-02-04 | — | — | US | disclosed |
| US-4428874-A | QUANTITATIVE ANALYSIS OF PROTEOLYTIC ENZYMES | PENTAPHARM A.G. (CH) | 1984-01-31 | — | — | US | disclosed |
| EP-0019589-A1 | Tripeptide derivatives and their use in a process for determining enzymes | Pentapharm A.G. (CH) | 1980-11-26 | — | — | EP | disclosed |