Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.54 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784395 | 0.91 | HDAC6 (0.72) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL11141720 | 0.90 | HDAC6 (0.77) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10884486 | 0.88 | HDAC6 (0.65) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10887379 | 0.87 | HDAC6 (0.70) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10888099 | 0.87 | HDAC6 (0.67) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10886652 | 0.87 | HDAC6 (0.70) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10892687 | 0.87 | HDAC6 (0.70) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8321305 | 0.87 | HDAC6 (0.55) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10888424 | 0.86 | HDAC6 (0.65) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL10887705 | 0.86 | HDAC6 (0.65) | HDAC6HDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4623662-A | ANTICHOLESTEROL, ANTILIPEMIC | AMERICAN CYANAMID COMPANY (US) | 1986-11-18 | — | — | US | disclosed |