Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412614 | 0.80 | MAPK1 (0.50) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL12525500 | 0.80 | NOX1 (0.49) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL7529692 | 0.80 | MAPK1 (0.50) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL11176800 | 0.77 | MAPK1 (0.51) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL11176798 | 0.77 | MAPK1 (0.51) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL29386255 | 0.77 | MAPK1 (0.51) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL19390275 | 0.77 | MAPK1 (0.44) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL11422823 | 0.76 | MAPK1 (0.58) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL11420875 | 0.76 | MAPK1 (0.58) | NOX1MAPK1GAAPOLBRAPGEF4 | |
| SCHEMBL21902750 | 0.74 | NOX1 (0.41) | NOX1MAPK1GAAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612395-A | Process for the production of N-(2-methyl-4-chlorophenyl)-formamidine derivatives | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| US-4612395-A | Process for the production of N-(2-methyl-4-chlorophenyl)-formamidine derivatives | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| US-4612395-A | Process for the production of N-(2-methyl-4-chlorophenyl)-formamidine derivatives | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |