Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891805 | 1.00 | CYP19A1 (1.00) | CYP19A1OR51E2 | |
| Plomestane SCHEMBL3434 | 0.89 | CYP19A1 (1.00) | CYP19A1OR51E2 | |
| Plomestane SCHEMBL9171652 | 0.89 | CYP19A1 (1.00) | CYP19A1OR51E2 | |
| Plomestane SCHEMBL1552197 | 0.89 | CYP19A1 (1.00) | CYP19A1OR51E2 | |
| Plomestane SCHEMBL29400102 | 0.89 | CYP19A1 (1.00) | CYP19A1OR51E2 | |
| SCHEMBL11228557 | 0.88 | CYP19A1 (0.78) | CYP19A1OR51E2 | |
| SCHEMBL11228561 | 0.88 | CYP19A1 (0.78) | CYP19A1OR51E2 | |
| SCHEMBL10480192 | 0.87 | CYP19A1 (0.77) | CYP19A1OR51E2 | |
| SCHEMBL10480169 | 0.87 | CYP19A1 (0.77) | CYP19A1OR51E2 | |
| SCHEMBL10480247 | 0.87 | CYP19A1 (0.77) | CYP19A1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104489-B1 | AMINOALKYL STEROIDS | G.D. Searle & Co. (US) | 1986-12-03 | — | — | EP | disclosed |
| US-4495102-A | Aminoalkyl steroids | G. D. SEARLE & CO. (US) | 1985-01-22 | — | — | US | disclosed |
| EP-0104489-A1 | Aminoalkyl steroids | G.D. Searle & Co. (US) | 1984-04-04 | — | — | EP | disclosed |