Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886838 | 1.00 | KDM4E (0.56) | KDM4EHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL10887028 | 1.00 | KDM4E (0.56) | KDM4EHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL10887592 | 1.00 | KDM4E (0.56) | KDM4EHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL10888698 | 1.00 | KDM4E (0.56) | KDM4EHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL10891067 | 1.00 | KDM4E (0.56) | KDM4EHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL9784469 | 0.93 | HDAC6 (0.53) | KDM4EHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL13911259 | 0.90 | KMT2A (0.63) | KDM4EKMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL29052342 | 0.90 | MEN1 (0.53) | KMT2AMEN1HPGDALDH1A1MAPK1 | |
| SCHEMBL10889513 | 0.88 | MEN1 (0.54) | KDM4EHDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL10886551 | 0.88 | MEN1 (0.54) | KDM4EHDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4623662-A | ANTICHOLESTEROL, ANTILIPEMIC | AMERICAN CYANAMID COMPANY (US) | 1986-11-18 | — | — | US | disclosed |