SCHEMBL10893199

SCHEMBL10893199

CCC[C@H]1CC[C@H](C2CCC(c3ccc(C4CCC([C@H]5CC[C@H](CCC)CC5)CC4)cc3)CC2)CC1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.63
ALDH1A1 P00352 1/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
MEN1 O00255 1/20 0.59
MAPK1 P28482 1/20 0.59
KMT2A Q03164 1/20 0.59
ESR2 Q92731 9/20 0.50
ESR1 P03372 6/20 0.44
CYP3A4 P08684 2/20 0.44
SPHK1 Q9NYA1 3/20 0.40
TLR4 O00206 1/20 0.40
CYP2D6 P10635 1/20 0.40
DRD2 P14416 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9159105 1.00 CYP2C9 (0.63) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9159091 1.00 CYP2C9 (0.63) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10893213 1.00 CYP2C9 (0.63) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10893211 1.00 CYP2C9 (0.63) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9159110 1.00 CYP2C9 (0.63) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9153193 0.94 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10893796 0.94 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10893795 0.94 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10893800 0.94 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9153200 0.94 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0084974-B1 CARBOCYCLIC COMPOUNDS WITH LIQUID-CRYSTAL PROPERTIES Chisso Corporation (JP) 1986-04-02 EP disclosed
US-4477369-A New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same CHISSO CORPORATION (JP) 1984-10-16 US disclosed
EP-0084974-A1 Carbocyclic compounds with liquid-crystal properties Chisso Corporation (JP) 1983-08-03 EP disclosed