Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 3/20 | 0.53 |
| ▸ | APAF1 | O14727 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893628 | 1.00 | TDP1 (0.62) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10893625 | 1.00 | TDP1 (0.62) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10889846 | 0.93 | NR1I2 (0.59) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10889844 | 0.93 | NR1I2 (0.59) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5161757 | 0.92 | TDP1 (0.75) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5161753 | 0.92 | TDP1 (0.75) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5484474 | 0.92 | TDP1 (0.75) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Bromide SCHEMBL10529250 | 0.91 | TDP1 (0.74) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Bromide SCHEMBL5161813 | 0.91 | TDP1 (0.74) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10895435 | 0.90 | TDP1 (0.58) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631274-A | MICROBIOCIDES | FUJISAWA PHARMCEUTICAL CO., LTD. (JP) | 1986-12-23 | — | — | US | disclosed |
| EP-0154354-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-11 | — | — | EP | disclosed |