Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.53 |
| ▸ | APAF1 | O14727 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.53 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893756 | 1.00 | TDP1 (0.53) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10675551 | 0.92 | TDP1 (0.63) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10675546 | 0.92 | TDP1 (0.63) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10895987 | 0.91 | TDP1 (0.63) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10895998 | 0.91 | TDP1 (0.63) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10674196 | 0.89 | TDP1 (0.49) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10674204 | 0.89 | TDP1 (0.49) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10671700 | 0.89 | TDP1 (0.49) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10671707 | 0.89 | TDP1 (0.49) | TDP1APAF1APEX1LMNATSHR | |
| SCHEMBL10893924 | 0.88 | TDP1 (0.69) | TDP1APAF1APEX1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631274-A | MICROBIOCIDES | FUJISAWA PHARMCEUTICAL CO., LTD. (JP) | 1986-12-23 | — | — | US | disclosed |
| EP-0154354-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-11 | — | — | EP | disclosed |