⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283630 | 1.00 | — | — | |
| SCHEMBL60554 | 1.00 | — | — | |
| Propane SCHEMBL2402465 | 0.93 | TDP1 (0.47) | — | |
| SCHEMBL7621808 | 0.83 | TDP1 (0.38) | — | |
| SCHEMBL13283474 | 0.79 | — | — | |
| SCHEMBL5907193 | 0.79 | — | — | |
| SCHEMBL5935859 | 0.79 | — | — | |
| SCHEMBL12139121 | 0.77 | TDP1 (0.53) | — | |
| SCHEMBL15456942 | 0.77 | TDP1 (0.53) | — | |
| SCHEMBL1926252 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12460234-B2 | Synthesis of isoprenoids and derivatives | WILLIAM MARSH RICE UNIVERSITY (US) | 2025-11-04 | — | — | US | disclosed |
| US-20240182932-A1 | SYNTHESIS OF ISOPRENOIDS AND DERIVATIVES | WILLIAM MARSH RICE UNIVERSITY (US) | 2024-06-06 | — | — | US | disclosed |
| US-20230202984-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-20210371884-A1 | SYNTHESIS OF ISOPRENOIDS AND DERIVATIVES | WILLIAM MARSH RICE UNIVERSITY | 2021-12-02 | — | — | US | disclosed |
| US-11046978-B2 | Synthesis of isoprenoids and derivatives | WILLIAM MARSH RICE UNIVERSITY (US) | 2021-06-29 | — | — | US | disclosed |
| US-20190352679-A1 | MICROBIAL SYNTHESIS OF ISOPRENOID PRECURSORS, ISOPRENOIDS AND DERIVATIVES INCLUDING PRENYLATED AROMATIC COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY | 2019-11-21 | — | — | US | disclosed |
| EP-3430151-A1 | MICROBIAL SYNTHESIS OF ISOPRENOID PRECURSORS, ISOPRENOIDS AND DERIVATIVES INCLUDING PRENYLATED AROMATICS COMPOUNDS | William Marsh Rice University (US) | 2019-01-23 | — | — | EP | disclosed |
| US-20180208575-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | PURDUE PHARMA L.P. | 2018-07-26 | — | — | US | disclosed |
| US-20180134690-A1 | INDAZOLES AND USE THEREOF | PURDUE PHARMA LP (US) | 2018-05-17 | — | — | US | disclosed |
| US-9878991-B2 | TRPV1 antagonists including dihydroxy substituent and uses thereof | PURDUE PHARMA L.P. (US) | 2018-01-30 | — | — | US | disclosed |
| US-20070135631-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-14 | — | — | US | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |
| EP-0819000-A4 | NODULISPORIC ACID DERIVATIVES | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| US-5962499-A | ACARICIDAL, ANTIPARASITIC, INSECTICIDAL AND ANTHELMINTIC AGENTS | MERCK & CO., INC. (US) | 1999-10-05 | — | — | US | disclosed |
| CN-1184423-A | Nodulisporic acid derivatives | MERCK & CO INC (US) | 1998-06-10 | — | — | CN | disclosed |
| EP-0819000-A1 | NODULISPORIC ACID DERIVATIVES | Merck & Co., Inc. (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996029073-A1 | NODULISPORIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1996-09-26 | — | — | WO | disclosed |
| EP-0031877-B1 | OPTICALLY ACTIVE 1,2-BIS-(DIPHENYLPHOSPHINO)-COMPOUNDS, METAL COMPLEXES CONTAINING THEM AS CHIRAL LIGANDS AND THEIR USE | Degussa Aktiengesellschaft (DE) | 1983-02-02 | — | — | EP | disclosed |
| US-4356324-A | CHIRAL LIGANDS FOR RHODIUM HYDROGENATION CATALYSTS | DEGUSSA AKTIENGESELLSCHAFT, A GERMAN CORP. (DE) | 1982-10-26 | — | — | US | disclosed |
| EP-0031877-A1 | Optically active 1,2-Bis-(diphenylphosphino)-compounds, metal complexes containing them as chiral ligands and their use | Degussa Aktiengesellschaft (DE) | 1981-07-15 | — | — | EP | disclosed |