Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.62 |
| ▸ | TTR | P02766 | 6/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.54 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10452818 | 0.94 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL11860605 | 0.94 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10452917 | 0.92 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10452916 | 0.92 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7542790 | 0.85 | ACSL1 (0.59) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL11768031 | 0.85 | TTR (0.56) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL11768716 | 0.85 | TTR (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10896617 | 0.85 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL1105126 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL10893810 | 0.84 | ACSL1 (0.61) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4626432-A | 7-HYDROXY-OR ALKOXYXANTHONE-2-CARBOXYLIC ACID | BURROUGHS WELLCOME CO. (US) | 1986-12-02 | — | — | US | disclosed |