Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.56 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066946 | 1.00 | SPHK1 (0.56) | SPHK1SPHK2DRD2LPLLIPG | |
| SCHEMBL4323763 | 0.94 | SPHK1 (0.61) | SPHK1SPHK2DRD2LPLLIPG | |
| SCHEMBL9184276 | 0.91 | SPHK1 (0.49) | SPHK1SPHK2DRD2 | |
| SCHEMBL10761093 | 0.91 | SPHK1 (0.49) | SPHK1SPHK2 | |
| SCHEMBL6746557 | 0.91 | ESR2 (0.50) | SPHK1SPHK2 | |
| SCHEMBL9349785 | 0.91 | SPHK1 (0.49) | SPHK1SPHK2 | |
| SCHEMBL9184282 | 0.91 | SPHK1 (0.49) | SPHK1SPHK2DRD2 | |
| SCHEMBL9499232 | 0.90 | CYP2C9 (0.54) | SPHK1SPHK2 | |
| SCHEMBL7576264 | 0.90 | CYP2C9 (0.54) | SPHK1SPHK2 | |
| SCHEMBL7507337 | 0.90 | CYP2C9 (0.54) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084974-B1 | CARBOCYCLIC COMPOUNDS WITH LIQUID-CRYSTAL PROPERTIES | Chisso Corporation (JP) | 1986-04-02 | — | — | EP | disclosed |
| US-4477369-A | New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same | CHISSO CORPORATION (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0084974-A1 | Carbocyclic compounds with liquid-crystal properties | Chisso Corporation (JP) | 1983-08-03 | — | — | EP | disclosed |